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CANNABINOID

CANNABIS

MEDIUM RISK
BEST FOR:Relaxation●●●●●○○○○○5/10
CANNABIS · MARIJUANA · WEED · POT · GRASS · HERB · MARY JANE · GANJA · DOPE · CHRONIC · CANNABIS SATIVA
CannabinoidPsychoactiveCB1 AgonistPlant-basedRecreational

Psychoactive plant containing THC and CBD; acts on endocannabinoid receptors producing euphoria, sedation, and altered perception.

ROUTE / DOSAGE
LOW2.5mg
STANDARD5-10mg
HIGH10-25mg
Note: Edibles - onset delayed and effects prolonged; dose refers to THC content
CYCLE
No strict cycle tolerance develops with daily use periodic breaks recommended
BIOAVAILABILITY
~10-35% oral ~50% inhaled
ACTIVE DURATION
2-8h (subjective)
STORAGE
Room temperature dry away from light
HALF-LIFE
20-30h (THC terminal) metabolites longer (plasma)
DURATION BREAKDOWN
Total1-8 hours
Onsetseconds-2h
Come up5-60 min
Peak30min-4h
Offset1-3 hours
After effects2-6 hours
Duration varies by route, dose, and individual. Source: community reports.
§ 01 — EFFECTS
8 documented
Euphoria and elevated mood
Altered time and sensory perception
Relaxation and sedation
Increased appetite
Impaired short-term memory
Dry mouth and red eyes
Tachycardia
Anxiety or paranoia at higher doses
§ 02 — RISKS
Cannabis use disorder with chronic use, particularly in adolescents and older adults
Cognitive impairment including deficits in attention, memory, and executive function
Psychiatric risks including psychosis, anxiety, and paranoia, especially with high-THC products
Perinatal and neurodevelopmental harm from prenatal or lactation exposure
Acute pediatric toxicity including encephalopathy, coma, and respiratory depression from unintentional ingestion
Impaired driving ability and increased motor vehicle accident risk
§ 03 — INTERACTIONS
No interaction with your stack
VIEW STACK
CAUTION
2C-T-x
2C-x
5-MeO-xxT
Amphetamines
aMT
Cocaine
DMT
DOx
LSD
Mescaline
Mushrooms
25x-NBOMe
AVOID · DANGEROUS
Lithium
§ 04 — SCIENCE

Cannabis contains over 560 identified constituents, with Δ9-THC responsible for most psychotropic effects and non-psychoactive cannabinoids like CBD, CBC, and CBG offering potential medicinal properties. Evidence for therapeutic use in conditions such as chronic pain, multiple sclerosis, and chemotherapy-induced nausea is moderate, while efficacy data in older adults remain lacking. Adolescent use is associated with chronic cognitive, psychosocial, psychiatric, and physical outcomes, and cannabis use disorder is well-documented across age groups. Prenatal exposure carries possible perinatal and longitudinal neurodevelopment risks. Acute pediatric toxicity can include encephalopathy, coma, and respiratory depression.

§ 06 — SOURCES
[1]
Phytochemistry of Cannabis sativa L.
pubmed.ncbi.nlm.nih.gov ↗
[2]
Cannabis and Pregnancy
pubmed.ncbi.nlm.nih.gov ↗
[3]
Cannabis sativa
pubmed.ncbi.nlm.nih.gov ↗
[4]
Cannabis Use Disorder in Adolescents
pubmed.ncbi.nlm.nih.gov ↗
[5]
Acute Cannabis Toxicity
pubmed.ncbi.nlm.nih.gov ↗
[6]
Cannabis Use and Misuse in Older Adults
pubmed.ncbi.nlm.nih.gov ↗
[7]
Cannabis-Impaired driving: ethical considerations
pubmed.ncbi.nlm.nih.gov ↗
[8]
Cannabis Use Disorder in Adolescents (Child Adolesc Psychiatr Clin N Am)
pubmed.ncbi.nlm.nih.gov ↗
[9]
PsychonautWiki - Cannabis
psychonautwiki.org ↗
Disclaimer. Protokol.wiki is an informational reference. Nothing on this site is medical advice. Compounds listed may be unapproved, unregulated, or illegal in your jurisdiction. Consult a licensed physician before use. Data compiled from peer-reviewed literature.
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