COMPOUNDS / STEROID / PRIMOBOLAN
STEROID

PRIMOBOLAN

MEDIUM RISK
BEST FOR:Cutting●●●●●●●○○○7/10
PRIMOBOLAN · METHENOLONE · METHENOLONE ACETATE · METHENOLONE ENANTHATE · PRIMOBOLAN DEPOT · PRIMO · METENOLONE · METHENOLONE
Anabolic SteroidDHT DerivativeCuttingInjectableOralMild Androgenic

Mild DHT-derived anabolic steroid with low androgenic activity, used primarily in cutting cycles; available as oral acetate and injectable enanthate.

ROUTE / DOSAGE
LOW50mg
STANDARD75-100mg
HIGH150mg
Note: Methenolone acetate; daily dosing required due to short half-life
CYCLE
8-12 weeks typical 6 weeks minimum oral
BIOAVAILABILITY
~20-30% oral ~100% IM
ACTIVE DURATION
12-24h oral 2-3 weeks IM (subjective)
STORAGE
Room temperature dry away from light protect from freezing
HALF-LIFE
6-8h oral acetate 10-14 days IM enanthate (plasma)
DURATION BREAKDOWN
Total12-24h oral, 2-3 weeks IM
Onset2-4h oral, 2-3 days IM
Come up1-2 weeks oral, 3-4 weeks IM
Peak2-4 weeks oral, 4-6 weeks IM
Offset1-2 weeks oral, 2-4 weeks IM
After effects2-4 weeks post-cycle both routes
Duration varies by route, dose, and individual. Source: community reports.
§ 01 — EFFECTS
6 documented
Mild anabolic gains
Low androgenic effects
Minimal water retention
Nitrogen retention
Anti-catabolic action
Low hepatotoxicity (oral form)
§ 02 — RISKS
Suppression of endogenous testosterone production requiring PCT
Adverse lipid profile changes (reduced HDL, elevated LDL)
Hepatotoxicity with oral form despite no 17-alpha alkylation
Virilization in female users
Androgenic effects including acne and hair loss in predisposed individuals
Cardiovascular strain with prolonged use
§ 03 — INTERACTIONS
Interaction data not yet available for this compound.
§ 04 — SCIENCE

Methenolone was developed in the 1960s and studied clinically for postoperative recovery, urological diseases, and hepatopathy, with early German and Japanese literature documenting its anabolic and anti-catabolic effects. Metabolite identification studies have characterized its urinary excretion profile, with 3α-hydroxy-1-methylen-5α-androstan-17-one as the major metabolite detectable for up to 5 days after a single 10 mg oral dose. Despite its reputation as a 'mild' steroid, robust controlled trials in athletic populations are essentially absent, and most dosing and efficacy data come from anecdotal bodybuilding experience rather than rigorous clinical research. Its low rate of aromatization and reduced androgenic profile are well-established pharmacologically, but long-term safety data in performance contexts remain limited.

§ 06 — SOURCES
[1]
PubMed PMID 14157558 - Clinical use of Primobolan for urological diseases
pubmed.ncbi.nlm.nih.gov ↗
[2]
PubMed PMID 13893391 - Methenolone enanthate in postoperative therapy
pubmed.ncbi.nlm.nih.gov ↗
[3]
PubMed PMID 6339822 - Detection of methenolone acetate urinary metabolite by isotope dilution mass spectrometry
pubmed.ncbi.nlm.nih.gov ↗
[4]
PubMed PMID 14050545 - Mechanism of action of Primobolan
pubmed.ncbi.nlm.nih.gov ↗
[5]
PubMed PMID 14218826 - Experimental investigation on anti-catabolic action of Primobolan
pubmed.ncbi.nlm.nih.gov ↗
[6]
PubMed PMID 2242348 - Identification of new urinary metabolites of methenolone acetate by GC/MS
pubmed.ncbi.nlm.nih.gov ↗
[7]
PubMed PMID 13949811 - Clinical use of Primobolan in hepatopathy
pubmed.ncbi.nlm.nih.gov ↗
[8]
PubMed PMID 5523648 - Age-related anabolic effect of Primobolan in animal experiments
pubmed.ncbi.nlm.nih.gov ↗
Disclaimer. Protokol.wiki is an informational reference. Nothing on this site is medical advice. Compounds listed may be unapproved, unregulated, or illegal in your jurisdiction. Consult a licensed physician before use. Data compiled from peer-reviewed literature.
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