KUDZU EXTRACT
Pueraria lobata root extract rich in isoflavones, traditionally used to reduce alcohol consumption and support cardiovascular health.
Multiple human trials demonstrate that kudzu extract reduces alcohol consumption in heavy drinkers without altering subjective intoxication or sleep architecture. In vitro studies show potent antioxidant and anti-inflammatory effects, including protection of endothelial cells against oxidative stress. Animal studies suggest hepatoprotective and anti-osteoporotic properties, though human evidence for these indications is limited. One mouse study raised concerns about potential hepatotoxicity with prolonged high-dose administration. Kudzu root extract also shows in vitro anti-HIV activity by blocking viral attachment, though clinical relevance is unproven.