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COMPOUNDS / NOOTROPIC / FASORACETAM
NOOTROPIC

FASORACETAM

LOW RISK
BEST FOR:Cognition●●●●●●○○○○6/10
FASORACETAM · NFC-1 · AEVI-001 · LAM 105 · NS 105 · MD-12
NootropicRacetamGABA-BADHDResearch Chemical

GABA-B upregulator used for cognitive enhancement and phenibut withdrawal support

ROUTE / DOSAGE
LOW5mg
STANDARD10-20mg
HIGH30mg+
CYCLE
4-8 weeks
BIOAVAILABILITY
~50% oral ~80% sublingual
ACTIVE DURATION
6-10h (subjective)
STORAGE
Room temperature dry away from light hydrate form sensitive to water loss
HALF-LIFE
4-6.5 hours (plasma)
DURATION BREAKDOWN
Total6-10 hours
Onset30min-1h
Come up30-60 min
Peak2-4 hours
Offset2-4 hours
After effects2-4 hours
Duration varies by route, dose, and individual. Source: community reports.
§ 01 — EFFECTS
5 documented
Upregulates GABA-B receptors
Reduces anxiety and social inhibition
Improves memory consolidation
May reverse phenibut tolerance
Mild cognitive enhancement
§ 02 — RISKS
Rebound anxiety if stopped abruptly after long use
Limited long-term human safety data
May cause fatigue at high doses
Potential interactions with GABAergic substances
§ 03 — INTERACTIONS
No interaction with your stack
VIEW STACK
CAUTION
Fasoracetam
§ 04 — SCIENCE

A 2016 open-label study in adolescents with ADHD and mGluR mutations showed significant improvements in attention and behavior after fasoracetam treatment. The compound modulates metabotropic glutamate receptors (mGluR) in addition to its GABAergic effects, which may explain its nootropic properties beyond simple anxiolysis. Preclinical studies in rodents demonstrate consistent memory-enhancing effects across multiple learning paradigms.

§ 05 — COMMUNITY REPORTS
!
ANECDOTAL — NOT PEER REVIEWED · self-reported data, sampling bias, and unverified doses.
“10mg sublingual completely eliminated my phenibut withdrawal anxiety within 3 days. Nothing else worked like this.”
r/nootropics
▲
847
UP
“Been using 15mg sublingual for 6 weeks. Focus is noticeably sharper and social anxiety basically gone. No tolerance issues so far.”
r/researchchemicals
▲
412
UP
“Used it during phenibut taper at 20mg/day. Made the process much more manageable. Week 3 was still rough but nothing unbearable.”
r/phenibut
▲
634
UP
§ 06 — SOURCES
[1]
Fasoracetam in adolescents with ADHD and glutamatergic gene network variants
pubmed.ncbi.nlm.nih.gov ↗
[2]
Memory-enhancing effects of fasoracetam in rodent models
pubmed.ncbi.nlm.nih.gov ↗
[3]
GABA-B receptor modulation by racetam nootropics
pubmed.ncbi.nlm.nih.gov ↗
Disclaimer. Protokol.wiki is an informational reference. Nothing on this site is medical advice. Compounds listed may be unapproved, unregulated, or illegal in your jurisdiction. Consult a licensed physician before use. Data compiled from peer-reviewed literature.
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