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COMPOUNDS / DISSOCIATIVE / PCP
DISSOCIATIVE

PCP

HIGH RISK
BEST FOR:Dissociation●●○○○○○○○○2/10
PCP · PHENCYCLIDINE · ANGEL DUST · SHERM · OZONE · ROCKET FUEL · EMBALMING FLUID · HOG · WACK · SERNYL · SERNYLAN
DissociativeNMDA AntagonistAnestheticSchedule IIHallucinogen

Potent dissociative anesthetic and NMDA antagonist originally developed for medical use, now known primarily for recreational misuse and severe psychological effects.

ROUTE / DOSAGE
LOW3mg
STANDARD5-10mg
HIGH10-15mg
CYCLE
No established safe cycle not recommended for any use
BIOAVAILABILITY
50-90% oral high intranasal/inhalation 100% IV
ACTIVE DURATION
4-8h (subjective)
STORAGE
Room temperature dry away from light controlled substance - store securely
HALF-LIFE
7-46h (plasma)
DURATION BREAKDOWN
Total4-8 hours
Onset2-90min
Come up20-120min
Peak1-3 hours
Offset2-4 hours
After effects2-24 hours
Duration varies by route, dose, and individual. Source: community reports.
§ 01 — EFFECTS
8 documented
Profound dissociation and derealization
Analgesia and anesthesia at higher doses
Hallucinations and distorted perception of body and space
Euphoria and stimulant-like effects at low doses
Impaired coordination and ataxia
Aggression, agitation, and paranoia at high doses
Nystagmus and slurred speech
Prolonged duration of action relative to other dissociatives
§ 02 — RISKS
Acute psychosis with potential for violent behavior and self-harm
Severe neurotoxicity with Olney's lesions demonstrated in animal models
Long-lasting schizophreniform symptoms persisting beyond acute intoxication
Respiratory depression and hypertensive crisis at high doses
Seizures and coma in overdose
Flashbacks and persistent cognitive impairment with chronic use
§ 03 — INTERACTIONS
No interaction with your stack
VIEW STACK
CAUTION
MXE
Caffeine
Opioids
AVOID · DANGEROUS
2C-T-x
ΑMT
5-MeO-xxT
DXM
GHB
GBL
Tramadol
MAOIs
DOx
Amphetamines
MDMA
Cocaine
Alcohol
Benzodiazepines
SSRIs
§ 04 — SCIENCE

PCP was originally developed in the 1950s as a surgical anesthetic but was discontinued for human medical use due to severe adverse psychological effects including agitation, hallucinations, and psychosis. Pharmacologically, it is one of the most potent NMDA antagonists among dissociative drugs, with a notably long half-life that contributes to prolonged and unpredictable effects. Research on PCP has been instrumental in the NMDA receptor hypofunction hypothesis of schizophrenia. Evidence for harm is robust, with well-documented cases of acute psychosis, violent behavior, and neurotoxicity at recreational doses. There are no established therapeutic applications in current clinical practice.

§ 06 — SOURCES
[1]
PsychonautWiki - PCP
psychonautwiki.org ↗
Disclaimer. Protokol.wiki is an informational reference. Nothing on this site is medical advice. Compounds listed may be unapproved, unregulated, or illegal in your jurisdiction. Consult a licensed physician before use. Data compiled from peer-reviewed literature.
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